Ekeler picked up the injury while trying to make a cut, and looked distraught when he made his way back to the bench. His status for Week 3 against the Raiders is very much up in the air, and it seems more likely than not that Jacorey Croskey-Merritt and Jeremy McNichols will handle the rushing attempts for that game against Las Vegas.

Not a surprise, as Reed looked to be in significant pain while hauling down a touchdown that was taken off the board due to penalty. The 25-year-old will need a lot of things to go right in order for him to play in Week 3 against the Browns.

Rodriguez’s absence once again clears the way for rookie Jacory Croskey-Merritt to lead the Commanders’ rushing attack. Austin Ekeler led the backfield with 33 offensive snaps last week, though, and is the favorite to do so again, operating in his typical receiving-heavy role. The Commanders also declared P Mitch Wishnowsky, QB Josh Johnson, LB Ale Kaho, LB Kain Medrano, T Trent Scott and T George Fant inactive.

The Packers’ vaunted defense will have its new star pass rusher on the field. Unfortunately, the Packers declared CB Bo Melton, S Zayne Anderson, RT Zach Tom (oblique), LG Aaron Banks (ankle/groin), TE Ben Sims and DL Warren Brinson inactive. Losing both Tom and Banks hurts Jordan Love’s protection. It would be unsurprising to see the Packers dial up quick-hitting pass plays to help reduce pressure from Washington’s pass rush. On the plus side, Packers CB Nate Hobbs (knee) is active.

Jennings is now on the wrong side of questionable. He will need to practice in some capacity tomorrow if he is to suit up for Week 2 against the Saints. Perhaps, the only redeeming aspect of the 49ers’ brutal week is that their opponent is about as soft as one can hope for. Ricky Pearsall and Christian McCaffrey will be leaned upon in this one.

Bowers is “hoping to play” in Week 2 against the Chargers, but said that “we’ll see how it’s feeling throughout the week.” The Raiders are understandably giving Bowers an extra day off, with this week’s game scheduled for Monday night. The elite TE1’s practice participation on Friday and Saturday can tell us far more about his availability than today’s absence. In the meantime, for those who currently have Bowers in their starting lineup, stashing No. 2 TE Michael Mayer on fantasy benches is worthwhile. In Week 1, Bowers landed hard on his left knee after taking a hit to the right knee while running along the sideline. He was later seen limping with his left leg, and sported a sleeve on the left leg at today’s practice. It appears as though the fall was more of an issue than the direct hit.

Gardner dealt with a reported calf injury in August before appearing on the Week 1 injury report with a fibula issue. He practiced in full yesterday and was not on the injury report at all. The development suggests Gardner suffered the injury in practice today, but its severity is currently unknown. The Jets are tasked with containing the Bills’ passing game this weekend. Hopefully, Gardner is able to practice in some capacity tomorrow.

We assume this will be a full session based on beat reporter quotes, but even if it was a limited, McCaffrey is well on track to play against the Saints on Sunday. He should get an easy RB1 workload and the 49ers will desperately need him to deliver production with George Kittle and Brock Purdy out and Jauan Jennings’ status still under some question.

Two limited sessions put London on track to play, but it also suggests he may be a little sore. London should again lead his team in target share against the Vikings. Downfield WR Darnell Mooney (shoulder) is trending toward making his 2025 debut, which should keep safeties honest against London. He’s a WR1 in Week 2.